Bhandari Research Group

Epigenetic Inheritance

Epigenetic modifications control how genetic information is expressed without altering genetic codes stored in DNA. Environmental exposures can positively or negatively influence epigenetic modifications, leading to alterations in physiological functions. Some alterations can be passed down to subsequent generations through non-genetic inheritance. Our laboratory studies gene-environment interactions, particularly how environmental stressors (chemical or non-chemical) induce epigenetic changes leading to adverse health outcomes. In research, we utilize animal models (fish and rodents), cell co-cultures (2D and 3D spheroids), human cell lines, and population-based studies. 

Interested in research?
Our laboratory seeks graduate students (M.S. and Ph.D.) to participate in environmental epigenetics, transgenerational health, and CRISPR-mediated epigenome editing research. Undergraduate students can register for Undergraduate Research in Biology courses [ BIO_SC 2950 (sophomore) and 4950/4952 (junior and senior)]. All interested students should contact Dr. Ramji Bhandari for further details.  If you are a potential graduate (Ph.D.) student and would like to apply for a fellowship to philanthropic foundations, NSF, or NIH, please contact Dr. Bhandari ahead of time. 

Office: 217a Lefevre Hall
Lab: 219 Lefevre Hall


Division of Biological Sciences
University of Missouri Columbia
1200 University Avenue
Columbia, MO 65211, U.S.A.